ポリアミノ プロピル ビグアニド
CAS Number: 32289-58-0; 27083-27-8;
PHMB hydrochloride; PHMB HCl;
PolyHexaMethylene Biguanide, hydrochloride;
Related Product:
CAS No.: 57028-96-3;
PHMG chloride (PolyHexaMethylene Guanidine, hydrochloride)
カチオン性広域抗菌剤であるPHMB塩酸塩は、細胞膜の活性を阻害することで殺菌目的を達成する。
PHMB hydrochloride, a cationic broad-spectrum antimicrobial agent, achieves bactericidal purpose by inhibiting cell membrane activity.
As a cell membrane active antimicrobial agent, PHMB inhibits bacterial activity better than that of fungi.
Antimicrobial mechanism is roughly as follows:
PHMB is a polymerized cationic compound, which is easily adsorbed by various types of bacteria that are usually negatively charged, thus inhibiting the division function of the bacteria and making the bacteria lose the ability to reproduce.
Technical Data:
| PHMB 20% Solution | PHMB Solid | |
| Appearance | Colorless clear to slightly pale yellow liquid | White to slight yellow hygroscopic powder |
| Odor | Characteristic | Characteristic |
| Turbidity [NTU] | Max. 10 | — |
| Solid component [％] | 19.0 to 21.0 | Min. 95.0 |
| Density at 20℃ [g/ml] | 1.039 to 1.050 | — |
| pH-Value at 25℃ | 4 to 6 | 4 to 7 |
| Absorbance value (1%, 237nm) | Min. 400 | Min. 400 |
| Absorbance ratio (237nm / 222nm) | 1.2 to 1.6 | 1.2 to 1.6 |
PHMB Features:
1. PHMB has the ability to inhibit Gram-positive bacteria, Gram-negative bacteria, fungi (many kinds of ringworm and mold) and yeast.
2. PHMB has rapid inhibitory effect on E. coli, Staphylococcus aureus and Candida albicans.
3. PHMB: LD50＞5000mg/kg, HPMB is skin friendly, human and environment friendly.
Areas of application:
PHMB is widely used in oil field chemicals, water treatment chemicals, daily chemicals, textile printing and dyeing, swimming pool disinfection, flower antiseptic treatment, animal husbandry, aquaculture, agriculture, pet antibacterial, soil improvement, environmental disinfection, disinfection products, etc.
In aquaculture, PHMB can rapidly inhibit Gram-negative bacteria, floating Vibrio, Vibrio parahaemolyticus, Vibrio algolyticus and other harmful bacteria in seawater, and has good preventive and therapeutic effects on various diseases caused by bacteria in South American white shrimp and other aquatic products.
PHMB Chemical Formula:
1. CAS# 32289-58-0 (EC# 687-569-4; 608-723-9);
(C8H17N5·ClH)n; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene), hydrochloride;
2. CAS# 27083-27-8 (EC# 608-042-7);
(C10H18N8·C6H16N2)x·xClH;
Guanidine, N,N”’-1,6-hexanediylbis[N’-cyano-, polymer with1,6-hexanediamine, hydrochloride;
3. CAS# 91403-50-8 (EC# 618-745-0);
IUPAC names: Poly(hexamethylenbiguanid)-hydrochlorid
PHMB Chemical Name:
Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene),hydrochloride;
Poly(hexamethylenebiguanide) hydrochloride;
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride;
Poly(hexamethylene diguanide) hydrochloride；
Poly[imino(carbonimidoyl)imino(carbonimidoyl)iminohexane-1,6-diyl] hydrochloride (1:?);
Guanidine,N,N”’-1,6-hexanediylbis[N’-cyano-,polymer with 1,6-hexanediamine, hydrochloride;
N,N”’-1,6-Hexanediylbis(N’-cyanoguanidine),hexamethylenediamine polymer, hydrochloride;
